Trolamine salicylate is a topical anti-inflammatory medicine that is used in the symptomatic treatment of pain in patients with arthralgias and arthritis, muscular sprains, and neuralgias.

Trolamine Uses:

• It is indicated for the symptomatic treatment of pain as occur in patients with rheumatism, muscular pains, sprains, neuralgia, and arthritis.

Trolamine dose in Adults

Trolamine dose in the treatment of Pain:

• Topical: It is applied topically to the affected area three or four times a day or as needed.

Trolamine dose in children:

• Children older than 12 years:

  • Refer to adult dosing.

Pregnancy risk category: N (not formally assigned)

• Some systemic absorption may occur when the drug is applied topically. You should use it with caution, and avoid the last trimester.
• It may be used cautiously in lactating mothers.

Use in kidney disease:

No dosage adjustments mentioned. Use with caution. 

Use in liver disease:

No dosage adjustments mentioned in patients with liver disease. Use with caution.

Side Effects of Trolamine:

• Central Nervous System:

  • Confusion
  • Drowsiness

• Gastrointestinal:

  • Diarrhea
  • Nausea
  • Vomiting

• Respiratory:

  • Hyperventilation

Contraindications and Warnings:

• Patients with hypersensitivity reactions to the drug, or any component of the formulation, should not take it.
• It should be used with caution in patients with bleeding disorders such as those with hemophilia and low platelet counts or those on concomitant vitamin K antagonist (warfarin) or other anticoagulant treatment.
• Patients with hyperthyroidism and diabetes should use it with caution.

Trolamine: Drug Interaction

Monitoring parameters:

• Monitor the response to treatment.

How to administer Trolamine?

• It is wrapped around the affected area loosely with an elastic bandage. 

Mechanism of action of Trolamine:

• It blocks the activity of cyclooxygenase enzymes, which results in inhibition of prostaglandins as well as thromboxanes from inflammatory cells.
•  It inhibits the release inflammatory cytokines by these cells at the source of inflammation. 

International Brand Names of Trolamine:

• Analgesic Creme Rub/Aloe
• Arthricream
• Asper-Flex
• Mobisyl
• Myoflex
• Tru-micin
• Ultracin T
• Biafine
• Radiopost

Trolamine Brand Names in Pakistan:

No Brands Available in Pakistan.