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Liver Failure

Dr. Ahmed Farhan, 4 years ago 1 Replies

What is the criteria for liver transplantation in patients with acute liver failure?

Kings college criteria for liver tranplantation.

AFL due to paracetamol

  • Arterial pH <7.3 after resuscitation and 24 h since ingestion

  • Three following criteria:

    • Hepatic encephalopathy grades 3–4

    • Serum creatinine >300 mol/L (3.4 mg(dl)

    • INR >6.5
ALF not due to paracetamol

  • INR >6.5

  • Three out of five following criteria:

    • Etiology: indeterminate etiology hepatitis, drug-induced hepatitis

    • Age <10 years or >40 years

    • Interval jaundice encephalopathy >7 days

    • Bilirubin >300 mol/L (17 mg/dl)

    • INR >3.5
Maria, 4 years ago
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