Dyclonine (Sucrets) is used as a topical anesthetic that is administered as oral lozenges or sprays prior to procedures such as endoscopy and laryngoscopy. It is also used for the symptomatic relief of oral and throat pain and cough in patients with pharyngitis and following inhalation of irritants or cold.

Dyclonine (Sucrets) Uses:

• Cough:

  • It is indicated for the temporary relief of cough caused by inhaled irritants and associated with a cold.

• Mouth and throat symptoms:

  • It is indicated for the temporary relief of oral and throat symptoms such as sore throat, pai, or irritation.

Adult dose:

Dyclonine (Sucrets) Dose in the treatment of Mouth and throat symptoms:

• Oral topical: Lozenge:
  • The lozenges should be slowly dissolved in the mouth. One lozenge may be dissoleved in the mouth every two hours as needed to a maximum of 10 lozenges/day.

Dose in children:

Dyclonine (Sucrets) Dose in the treatment of Mouth and throat symptoms: 

• Lozenges 2 mg:

  • Children ≥6 years and Adolescents:
    • Slowly dissolve one lozenge in mouth every two hours or as required to a maximum daily dose of 10 lozenges.

• Lozenge 2 mg (with menthol 5 mg and pectin 6 mg):

  • Children ≥4 years and Adolescents:
    • Slowly dissolve one lozenge in mouth every two hours or as required to a maximum daily dose of 10 lozenges.

• Lozenge 3 mg (with menthol 6 mg):

  • Children ≥4 years and Adolescents:
    • Slowly dissolve one lozenge in mouth every two hours or as required to a maximum daily dose of 10 lozenges.

Use in Pregnancy and Lactation:

No dosage adjustments recommended. Since it is used as a topical anesthetic, it may be used safely during pregnancy and lactation. 

Dose in Kidney disease:

No dosage adjustments have been provided in the manufacturer's labeling. 

Dose in Liver disease:

No dosage adjustments have been provided in the manufacturer's labeling. 

Side effects of Dyclonine (Sucrets):

• Central Nervous System:

  • Feeling Hot
  • Localized Numbness
  • Localized Warm Feeling
  • Sensation Of Cold

• Gastrointestinal:

  • Burning Sensation Of Mouth

• Hypersensitivity:

  • Hypersensitivity Reaction

• Local:

  • Local Irritation
  • Local Pain

Contraindications and Warnings:

None mentioned. 

Dyclonine: Drug Interaction

Note: Drug Interaction Categories:

• Risk Factor C: Monitor When Using Combination
• Risk Factor D: Consider Treatment Modification
• Risk Factor X: Avoid Concomitant Use

  Risk Factor C (Monitor therapy).
  Methemoglobinemia associative Agents	Local anesthetics may have a greater adverse/toxic impact. Methemoglobinemia risk may increase.

Monitoring parameters:

Monitor for the response to treatment, cough reflex and gag reflex.

How to administer Dyclonine (Sucrets)?

It is administered as oral lozenges. The oral lozenges should be allowed to slowly dissolve in mouth. 

Mechanism of action of Dyclonine (Sucrets):

When applied over the mucous membranes, it acts as a local anesthetic and blocks the transmission of pain stimuli. 

International Brand names of Dyclonine [Ref]:

Dyclonine Brands Names in Pakistan:

• No Brands Available in Pakistan.